Buy 3-MEO-PCE Online
3-Methoxyeticyclidine (otherwise called Methoxieticyclidine and 3-MeO-PCE) is a novel dissociative substance of the arylcyclohexylamine class that produces dissociative and psychedelic impacts when managed. It is an auxiliary simple of PCE.
3-MeO-PCE started to pick up prominence in 2010 and is sold on the online hazy area investigate compound market as a legitimate option in contrast to PCP or ketamine.
Almost no information exists about the pharmacological properties, digestion, and poisonous quality of 3-MeO-PCE, and it has an extremely concise history of human use. It is firmly suggested that one use hurt decrease rehearses if utilizing this substance.
3-MeO-PCE, or N-Ethyl-1-(3-methoxyphenyl)cyclohexan-1-amine, is classed as an arylcyclohexylamine sedate. Ayrlcyclohexylamine drugs are named for their structures which incorporate a cyclohexane ring bound to a sweet-smelling ring alongside an amine gathering. 3-MeO-PCE contains a phenyl ring with a methoxy (CH3-O-) substituent at R3 attached to a cyclohexane ring. Bound to a similar carbon (R1) of the cyclohexanone ring is an amino ethyl chain – NCH2CH3. 3-MeO-PCE, as MXE, contains an amino ethyl chain as opposed to the amino methyl chain found in DCK and ketamine. 3-MeO-PCE is practically equivalent to MXE, however does not have a R2 subbed ketone. It is likewise homologous to 3-MeO-PCP yet comes up short on the extra carbons to finish a piperidine ring.
Additional data: NMDA receptor enemy
3-MeO-PCE acts chiefly as a NMDA receptor foe. NMDA receptors take into account electrical signs to go between neurons in the mind and spinal section; for the signs to pass, the receptor must be open. Dissociatives close the NMDA receptors by blocking them. This disengagement of neurons prompts loss of feeling, trouble moving, and in the long run a practically indistinguishable likeness the popular “k-opening.”
3-MeO-PCE has Ki estimations of 61 nM for the NMDA receptor, 743 nM for the dopamine transporter, 2097 nM for the histamine H2 receptor, 964 nM for the Alpha-2A adrenergic receptor, 115 nM for the serotonin transporter, 4519 nM for the σ1 receptor and 525 nM for the σ2 receptor.
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